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2013年5月Trends in Genetics期刊封面亮点

来源:未知 编辑:admin 发布时间:2017-08-14
2013年5月Trends in Genetics期刊封面亮点

2013年5月Trends in GENEtics期刊封面图片显示的是酵母菌属的程式化进化分支图。一种经典的方法来跟踪遗传和分子在进化过程中的变化是比较关系密切和较远物种相互关系。目前这中方法可以在许多物种全基因组水平中实现,产生了进化基因组学领域。研究人员综述了酵母菌属,包括一个最新的分类学,并且证明对这个属的研究,遗传上的处理有机体是进化基因组学的首选理想模型。封面图片显示的是酵母菌属的程式化进化分支图。

原文摘要:

Saccharomyces diversity and evolution: a budding model genus

Chris Todd Hittinger

Saccharomyces cerevisiae is one of the best-understood and most powerful genetic model systems. Several disciplines are now converging to turn Saccharomyces into an exciting model genus for evolutionary genetics and genomics. Yeast taxonomists and ecologists have dramatically expanded and clarified Saccharomyces diversity, more than doubling the number of bona fide species since 2000. High-quality genome sequences are available (or soon will be) for all seven known species. Haploid laboratory strains are enabling a deep integration of classic genetic approaches with modern genomic tools. Population genomic surveys and quantitative trait mapping of variation within species are underway across the genus. Finally, several case studies have Illuminated general and novel genetic mechanisms of evolution. Expanding strain collections, low-cost genome sequencing, and tools for precise genetic manipulation promise to usher in a golden era for this surprisingly diverse genus as an evolutionary model.

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